Wellbutrin XL (Bupropion Hydrochloride XL)

Wellbutrin XL (Bupropion Hydrochloride XL)

Product information

Wellbutrin XL (bupropion hydrochloride extended-release) is a medication used for the treatment of major depressive disorder (MDD) and seasonal affective disorder (SAD).

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Wellbutrin XL (Bupropion Hydrochloride) Tablets

Wellbutrin XL (Bupropion Hydrochloride) Tablets

Wellbutrin XL, with the active ingredient Bupropion Hydrochloride, is an extended-release antidepressant used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It belongs to the aminoketone class and works by affecting neurotransmitters in the brain to improve mood, energy levels, and overall mental health. Wellbutrin XL is taken once daily and provides consistent symptom relief throughout the day.


Key Information:

  • Form: Extended-release tablets, taken orally.
  • Strength: Available in 150mg tablets.
  • Indications: Treatment of depression and prevention of seasonal affective disorder.
  • Dosing: Typically taken once daily, with or without food.

Mechanism of Action

Wellbutrin XL works by inhibiting the reuptake of norepinephrine and dopamine, two neurotransmitters involved in mood regulation. By increasing their availability in the brain, it helps alleviate symptoms of depression and improve energy levels.


Uses of Wellbutrin XL

  • Major Depressive Disorder (MDD): Effectively treats symptoms of depression.
  • Seasonal Affective Disorder (SAD): Prevents depression episodes during specific seasons.

Common and Serious Side Effects

  • Common Side Effects: Dry mouth, headache, weight loss, nausea, and insomnia.
  • Serious Side Effects: Seizures, severe mood changes, or suicidal thoughts. Contact your doctor immediately if severe side effects occur.

How to Take Wellbutrin XL

  • Dosage: Wellbutrin XL is typically taken once daily in the morning to minimize insomnia. The dosage depends on your condition and response to treatment.
  • Administration: Swallow tablets whole. Do not crush, chew, or split them, as this can release the medication all at once, increasing the risk of side effects.

Patient Guidelines

  • Inform your doctor of any history of seizures, eating disorders, or alcohol/substance abuse.
  • Avoid alcohol, as it can increase the risk of seizures when combined with Wellbutrin XL.
  • Do not abruptly stop taking Wellbutrin XL without consulting your doctor, as withdrawal symptoms may occur.

Where to Store Wellbutrin XL

Store Wellbutrin XL tablets at room temperature (68°F to 77°F or 20°C to 25°C) in their original container. Protect from moisture and heat. Keep out of reach of children and pets. Dispose of expired medication responsibly.


Effectiveness and Reliability

Wellbutrin XL is a clinically proven antidepressant that effectively treats depression and seasonal affective disorder. Its once-daily extended-release formulation ensures consistent symptom control and improved quality of life.


Common Issues and Troubleshooting

  • If you miss a dose, skip it and take your next dose at the regular time. Do not double up.
  • Contact your doctor if you experience severe mood changes or suicidal thoughts.
  • Monitor for unusual changes in weight or energy levels during treatment.

References