Trulance (Plecanatide)

Trulance (Plecanatide)

Plecanatide

Product information

Trulance (Plecanatide) is a medication used to treat chronic idiopathic constipation and irritable bowel syndrome with constipation in adults.

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Trulance (Plecanatide) 


Trulance, with the active ingredient Plecanatide, is a prescription medication used to treat certain types of bowel disorders. It is primarily prescribed for chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) in adults. Plecanatide is a guanylate cyclase-C agonist that works by increasing intestinal fluid secretion and transit, facilitating bowel movements.  

Indications

  • Chronic Idiopathic Constipation (CIC) in adults.
  • Irritable Bowel Syndrome with Constipation (IBS-C) in adults.

Dosage and Administration:

  • The recommended dose is 3 mg taken orally once daily, with or without food.
  • Tablets should be swallowed whole, not crushed or chewed.
  • For patients unable to swallow tablets, the tablet can be crushed and mixed with water or soft foods.

Contraindications:

  • Patients under 6 years of age due to the risk of serious dehydration.
  • Patients with known or suspected mechanical gastrointestinal obstruction.

Precautions:

  • Use with caution in patients with severe renal impairment or severe hepatic impairment.
  • Avoid use in patients 6 years to less than 18 years of age.
  • Monitor for signs of excessive diarrhea or dehydration.

Side Effects:

Common side effects may include:
  • Diarrhea
  • Abdominal pain
  • Nausea
  • Headache
  • Increased gas
  • Dizziness

Overdose:

  • Overdose may lead to severe diarrhea and potential dehydration.
  • In case of overdose, contact poison control or seek emergency medical attention immediately.

Storage:

  • Store at room temperature, away from moisture and heat.
  • Keep the medication in its original container, tightly closed, and out of reach of children.

Additional Information:

  • Not recommended for use in pregnant or breastfeeding women unless deemed necessary by a healthcare provider.
  • Patients should be advised to maintain adequate hydration while taking Trulance.