Januvia (Sitagliptin) Tablets

Januvia, with the active ingredient Sitagliptin, is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage Type 2 diabetes. By increasing insulin production and decreasing the amount of glucose made by the liver, Januvia helps improve blood sugar control in adults. It is typically prescribed alongside a proper diet and exercise program and may be used alone or with other medications for diabetes.

Key Information:

• Form: Oral tablet, taken by mouth.
• Strengths: Available in 100mg tablets.
• Indications: Type 2 diabetes management.
• Dosing: Typically taken once daily, with or without food.

Mechanism of Action

Januvia works by inhibiting the enzyme DPP-4, which breaks down incretin hormones. These hormones help increase insulin release after meals and decrease the production of glucose by the liver. This action helps lower blood sugar levels effectively, particularly after meals and throughout the day.

Uses of Januvia

• Type 2 Diabetes Management: Helps improve blood sugar control in adults when combined with diet and exercise.
• Combination Therapy: Can be used with other diabetes medications like metformin or insulin for enhanced glucose control.

Common and Serious Side Effects

• Common Side Effects: Headache, upper respiratory tract infections, and nasal congestion.
• Serious Side Effects: Pancreatitis, kidney problems, and severe allergic reactions. Seek immediate medical attention if you experience symptoms like severe abdominal pain or swelling of the face and throat.

How to Take Januvia

• Dosage: Januvia is typically taken once daily at a dose of 100mg. The dosage may be adjusted by your healthcare provider based on your kidney function.
• Administration: Can be taken with or without food. Take it at the same time each day for consistent blood sugar control.

Patient Guidelines

• Inform your healthcare provider about any history of kidney disease or pancreatitis before starting Januvia.
• Notify your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Continue to monitor your blood sugar levels regularly and follow your prescribed diabetes management plan.

Where to Store Januvia

Store Januvia tablets at room temperature (68°F to 77°F or 20°C to 25°C) in their original container. Protect from moisture and light. Keep out of reach of children and pets. Do not use expired medication, and dispose of unused tablets safely.

Effectiveness and Reliability

Januvia has been clinically proven to improve blood sugar control in adults with Type 2 diabetes. Its once-daily dosing and compatibility with other diabetes medications make it a reliable choice for long-term management.

Common Issues and Troubleshooting

• If you miss a dose, take it as soon as you remember unless it’s close to your next dose. Do not double up.
• Monitor for signs of low blood sugar (e.g., dizziness, sweating, shaking) when used with other diabetes medications.
• Discuss any concerns or side effects with your healthcare provider promptly.

References

• WebMD - Januvia Overview
• Healthline - Januvia Uses and Side Effects
• Drugs.com - Januvia Information

Your healthcare provider will prescribe Januvia (100mg) to be taken once daily. Take the tablet at the same time each day, with or without food. Store Januvia at room temperature and keep it in its original container to protect it from moisture and light. Monitor blood sugar levels regularly, and contact your doctor if you experience unusual symptoms such as abdominal pain or severe allergic reactions.