Linzess (Linaclotide)

Linzess (Linaclotide)


Product information

Linzess (linaclotide) is a medication used to treat certain types of constipation, specifically chronic idiopathic constipation and irritable bowel syndrome with constipation. It works by increasing fluid secretion in the intestines, which softens stools and promotes bowel movements.

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linzess generic

Linzess (Constella in Canada)

Linzess, known as Constella in Canada, is a medication used for the treatment of certain types of constipation.

Generic Name:

  • Linaclotide


    • Treatment of irritable bowel syndrome with constipation (IBS-C).
    • Treatment of chronic idiopathic constipation (CIC).

How to Use:

  1. Dosage: Follow the doctor's prescription. Typically taken once daily on an empty stomach, at least 30 minutes before the first meal of the day.
  2. Administration: Swallow capsules whole; do not crush or chew.
  3. Duration: As prescribed by the healthcare provider. Effectiveness should be evaluated periodically.

Side Effects:

  • Common: Diarrhea, abdominal pain, gas, bloating, headache.
  • Serious: Severe diarrhea leading to dehydration, severe allergic reactions (rash, itching, swelling, dizziness, trouble breathing).
  • Note: This is not a comprehensive list of side effects. Patients should report any unusual or bothersome symptoms to their doctor.


  • Not for use in children under 18 years of age.
  • Avoid if you have a known allergy to linaclotide or any component of the formulation.
  • Caution in patients with severe gastrointestinal conditions.


  • Inform your doctor of all medications you are taking, as interactions with other drugs can occur.
  • No known significant food interactions.


  • Store at room temperature away from light and moisture.
  • Keep out of reach of children.